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United States

US 12,702,706 B2

Methods of preparing anti-human papillomavirus antigen T cells

US 12,702,706 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-11. Applicant: The United States of America,as represented by the Secretary,Department of Health and Human Services. Its PDF downloads from this page without an account, up to 5 a day.

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Applicant
The United States of America,as represented by the Secretary,Department of Health and Human Services
Inventors
Christian S. Hinrichs; Steven A. Rosenberg
Publication date
2026-08-11
Filing date
2024-02-01
Document type
B2 Granted patent
Also written as
US 12,702,706 B2 · US12702706 · 12702706

Abstract

Disclosed are methods of preparing an isolated population of human papillomavirus (HPV)-specific T cells comprise dividing an HPV-positive tumor sample into multiple fragments; separately culturing the multiple fragments; obtaining T cells from the cultured multiple fragments; testing the T cells for specific autologous HPV-positive tumor recognition; selecting the T cells that exhibit specific autologous HPV-positive tumor recognition; and expanding the number of selected T cells to produce a population of HPV-specific T cells for adoptive cell therapy.…

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Patent office website: United States Patent and Trademark Office (USPTO)

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