United States
US 12,702,720 B2
Genomic insulator element exhibiting enhancer blocking activities in lymphocytes and uses thereof
US 12,702,720 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-11. Applicant: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. Its PDF downloads from this page without an account, up to 5 a day.
- Applicant
- ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC.
- Inventors
- Sheng ZHOU; Brian SORRENTINO; Yong CHENG
- Publication date
- 2026-08-11
- Filing date
- 2022-11-10
- Document type
- B2 Granted patent
- Also written as
- US 12,702,720 B2 · US12702720 · 12702720
Abstract
A construct including a genomic insulator element that exhibits strong enhancer blocking activities in T lymphocytes is provided as are host cells, pharmaceutical compositions and methods of using the construct in the treatment of disease, in particular a disease to be treated with a retroviral vector-modified T lymphocyte.
The opening of the abstract. The full text is in the PDF.
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Patent office website: United States Patent and Trademark Office (USPTO)
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