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United States

US 12,702,730 B2

Engineered cartilage

US 12,702,730 B2 is a granted patent from the United States Patent and Trademark Office (USPTO), dated 2026-08-11. Applicant: STEMCELLAGO INC. Its PDF downloads from this page without an account, up to 5 a day.

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Applicant
STEMCELLAGO INC.
Inventors
Adetola Bamidele ADESIDA; Martin OSSWALD; Khalid ANSARI; Hadi SEIKALY
Publication date
2026-08-11
Filing date
2022-04-27
Document type
B2 Granted patent
Also written as
US 12,702,730 B2 · US12702730 · 12702730

Abstract

It is provided a method of producing high-quality engineered cartilage graft in a human of animal, such as nasal cartilage graft, comprising expanding chondrocytes and/or chondroprogenitors, e.g. autologous human nasoseptal chondrocytes (hNC,) from a donor patient by selecting expanded chondrocytes and/or chondroprogenitors by detecting the expression of at least one surfaceome protein gene or secretome protein gene, wherein the at least one surfaceome protein gene is ADGRG1, NPR3, SLC16A4, TSPAN13, FZD4 and SLC22A23 and the at least one secretome protein gene is ADGRG1, B3GNT7, COLGALT2, IGFB…

The opening of the abstract. The full text is in the PDF.

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